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Описание

Uldana Dildabayeva
Email: dildabaevauldana@gmail.com
Phone: (+7) - 705 - 851 - 69 - 34
Address: Astana, Kazakhstan


I am a Researcher who wants to contribute to cancer research. I hold a master’s degree in Biosciences
and Biomedical Engineering from the University of Grenoble Alpes and bachelor’s degree in Genetics from the
Al - Farabi Kazakh National University.
During my internship at the Centre for Genomic Regulation in Barcelona, I have worked on pancreatic
cancer adaptation mechanisms. At the Institute of Genetics and Cytology in Almaty I have identified novel
genetic mutations associated with breast cancer in Kazakh women population.
My research interests lie on cancer research, particularly in drug discovery , developing new targeted
therapies and identifying novel biomarkers
EDUCATION
University of Grenoble Alpes/ Erasmus Mundus Joint Programme
Master’s degree in Biosciences and Biomedical Engineering in Precision Medicine ( BeInPM)
Grade 15.88/20
Receieved full merit - based scholarship from Erasmus Mundus
Grenoble,
France
Sep 2023 -
Aug 2024
Al - Farabi Kazakh National University
Bachelor’s degree in Genetics
GPA 3.79/4
Received full merit - based scholarship from Kazakhstan Government
Almaty,
Kazakhstan
Sep 2019 -
Jun 2023
WORK EXPERIENCE & INTERNSHIPS
Nazarbayev University School of Medicine (NUSOM)
Research Assistant
Project: “Search for new therapeutic targets in antitumor therapy for breast cancer by genome -
wide screening using the CRISPR method”
Responsibilities:
• D esigning, optimizing, and conducting genome - wide CRISPR knockout/activation
screens to identify novel therapeutic targets in breast cancer.
• I dentifyin g secon d - li n e treatment for patients with Triple Negat ive Breast Cance r gaining
resi stance to PARPi
Astana,
Kazakhstan
Sep 2024 -
Present

Centre for Genomic Regulation (CRG)
Master’s Internship/Research Assistant
Project: " Adaptation to ARF6 - depletion in KRAS - driven PDAC is abolished by targeting TLR2 "
Responsibilities:
• Developed and conducted cell and molecular biology experiments to study the effects of
ARF6 and TLR2 - depletion in KRAS - driven pancreatic cancer cells.
• Drafted and optimized experimental protocols to improve reproducibility.
• Analyzed experimental data using R programming to validate findings.
Barcelona,
Spain
Jan 2024 -
July 2024

Institute of Genetics and Cytology
Laboratory Assistant /Volunteer
Project : “Determination of genetic predisposition to early breast cancer in women of Kazakh
ethnicity”
Responsibilities:
• Investigated novel genetic variants, particularly focused on the CHEK2 gene in breast
cancer patients in Kazakhstan.
A lmaty,
Kazakhstan
Feb 2022 -
Jun 2023

TRAINING & CERTIFICATIONS
European Scientific Institute
Summer School “Precision Oncology”
Results: Developed a medical device aimed at removing residual cancer cells following
melanoma surgery. Demonstrated strong leadership skills in project development.
Archamp s ,
France
September
2023
European Scientific Institute
Summer School “Computational Medicine”
Results: Created a device designed to improve the quality of life for patients with Chronic
obstructive pulmonary disease (COPD). Awarded 1st place for innovative project idea.

Archamps,
France
July 2024
King Abdullah University of Science and Technology (KAUST)
Course “Fundamental Skills in Bioinformatics”
Online

Results: Gained practical skills in data analysis, including programming in R and Python and basic
statistical concepts.
Stanford Medicine
Course “Writing in the Sciences”
Results: Enhanced scientific writing skills effective writing, manuscript formatting, peer review,
grаntwriting, and writing for general audiences through practical exercises.
Online
World Health Organization
Course “Next Generation Sequencing (NGS) for Influenza and SARS - CoV - 2”
Results: Acquired in - depth knowledge of NGS technology, workflow from sample preparation and
data upload in public databases.
Online
EXTRACURRICULAR ACTIVITIES
Public Association “Sunkar” Trade Union of Students
Project Coordinator
• Assisted students from low - income families by arranging transportation and providing free
lunches at the university.
Almaty,
Kazakhstan
Sep 2019 -
Dec 2020
“Komek” Student Community
Volunteer
• Provided academic support to children in orphanages, including homework assistance.
Organized concerts and fundraising events to collect donations for socially vulnerable
groups.
Almaty,
Kazakhstan
Jan 2020 -
Aug 2021
BI Group
Community Volunteer
• Conducted surveys to gather information on residents' needs and suggestions for
improving city life. Analyzed survey responses and analyzed data to guide development
and social improvement initiatives.
Shymkent,
Kazakhstan
June 2021

"Komek" Student Community
Digital Volunteer
• Assisted students with internet - related issues during COVID - 19. Supervised students
during online exams and coordinated with examiners and responsible personnel to ensure
smooth exam administration.
Almaty,
Kazakhstan
December
2020

SKILLS
Soft Skills:
Problem - solving (troubleshooting experimental protocols); Attention to Detail (recording and
analyzing data); Resilience (managing complex projects ); Adaptability (quickly adjusting to new
research methodologies or lab technologies)
Languages:
Kazakh (native) ; English (fluent); Spanish (elementary proficiency) ; Russian (advanced)
IELTS Academic 7.0 (Listening: 7.5; Reading: 7.5; Writing: 6.0; Speaking: 7.0)
Laboratory Skills:
• Cell Culture Techniques :
2D Cell Culture, 3D Cell Culture, Cell Viability Assay, Cell Proliferation Assay ; experience
with cell lines such as Pancreatic cancer ( MiaPaCa2 ), Triple - Negative Breast Cancer
( MDA - MB - 231; MDA - MB - 436; MDA - MB - 468 ) and Embryonic kidney ( HEK293 ) .
• Molecular Biology Techniques :
DNA Extraction, RNA Extraction, Protein Extraction, Protein Quantification, PCR, Primer
Design for PCR, RT - qPCR
• Protein Analysis :
Western Blot, Immunofluorescence
• Genetic Engineering and Viral Techniques :
Competent Cell Preparation, Bacterial Transformation, Lentivirus Production, Lentiviral
Infection, Gene Editing with shRNA, CRISPR - Cas9 Screening ; CRISPR Activation and
Inhibition (CRISPRa/CRISPRi)
Research Skills:
• Literature Review; Experimental Design; Data Collection; Data Interpretation;
Critical Thinking; Scientific Writing; Research Methodology; Drafting and Optimizing
Protocols; Collaboration with multidisciplinary teams; Conference Presentation
Computer Skills:
• R Programming; MS Office Suite (Word, Excel, PowerPoint); Google Workspace (Docs,
Sheets, Slides); data visualization tools (e.g., GraphPad Prism) .